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Tomohiro Asakawa Associate Professor

Publications

Synthesis of chemical-biology tools enabling in vivo imaging and analysis of epigallocatechin gallate., T. Asakawa, A. Yoshida, Y. Hirooka, T. Suzuki, K. Itoh, K. Shimizu, N. Oku, T. Furuta, T. Wakimoto, M. Inai, T. Kan, Heterocycles, 93, 218–242 (2016).
Syntheses of methylated catechins and theaflavins using 2-nitrobenzenesulfonyl group to protect and deactivate phenol., T. Asakawa, Y. Kawabe, A. Yoshida, Y. Aihara, T. Manabe, Y. Hirose, A. Sakurada, M. Inai, Y. Hamashima, T. Furuta, T. Wakimoto, and T. Kan, J. Antibiot., 69, 299-312 (2016).
Practical Synthesis of Kainoids: A New Chemical Probe Precursor and a Fluorescent Probe., S. Sasaki, H. Suzuki, H. Ouchi, T. Asakawa, M. Inai, R. Sakai, K. Shimamoto, Y. Hamashima, and T. Kan, Org. Lett., 16, 564-567 (2014).
The source of "Fairy Rings": 2-azahypoxanthine and its metabolite found in a novel purine metabolic pathway in plants., J.-H. Choi, T. Ohnishi, Y. Yamakawa, S. Takeda, S. Sekiguchi, W. Maruyama, K. Yamashita, T. Suzuki, A. Morita, T. Ikka, R. Motohashi, Y. Kiriiwa, H. Tobina, T. Asai, S. Tokuyama, H. Hirai, N. Yasuda, K. Noguchi, T. Asakawa, S. Sugiyama, T. Kan, and H. Kawagishi, Angew. Chem. Int. Ed., 53, 1552 (2014).
Enantioselective Synthesis of SB-203207., Y. Hirooka, K. Ikeuchi, Y. Kawamoto, Y. Akao, T. Furuta, T. Asakawa, M. Inai, T. Wakimoto, T. Fukuyama and T. Kan, Org. Lett., 16, 1646-1649 (2014).
Use of positron emission tomography for real-time imaging of biodistribution of green tea catechin, K. Shimizu, T. Asakawa, N. Harada, D. Fukumoto, H. Tsukada, T. Asai, S. Yamada, T. Kan, and N. Oku, PLOS ONE, 9, e85520 (2014).
PET Imaging Investigation of Nobiletin Based on a Practical Total Synthesis., T. Asakawa, A. Hiza, M. Nakayama, M. Inai, D. Oyama, H. Koide, K. Shimizu, T. Wakimoto, N. Harada, H. Tsukada, N. Oku, and T. Kan, Chem. Commun., 47, 2868-2870 (2011).
Proof of the existence of an unstable amino acid, pleurocybellaziridine, in Pleurocybella porrigens (angel’s wing mushroom)., T. Wakimoto, T. Asakawa, S. Akahoshi, T. Suzuki, K. Nagai, H. Kawagishi, and T. Kan, Angew. Chem. Int. Ed. 50, 1168-1170 (2011).
Reaction Behavior of Cumulene: Diels-Alder, Friedel-Crafts, and Pd-Catalyzed Domino Reactions., T. Asakawa, M. Iinuma, Y. Wakasugi, M. Kuno, T. Furuta, S. Fujii, K. Tanaka, and T. Kan, Heterocycles, 80, 1125-1147 (2010)
Domino Heck-C-H-Activation Reaction of Unsymmetrically Substituted [3]Cumulene. T. Furuta, T. Asakawa, M. Iinuma, S. Fujii, K. Tanaka and T. Kan. Chem. Commun., 3648-3650 (2006)
Reaction behavior of cumulene on Diels-Alder and Friedel-Crafts reaction., T. Asakawa, M. Iinuma, T. Furuta, S. Fujii, T. Kan and K. Tanaka, Chem. Lett., 512-513 (2006)

Review Articles

Chemical synthesis of tea polyphenols and related compounds: T. Asakawa, Y. Hamashima, T. Kan, Current Pharmaceutical Design, 19, 6207–6217 (2013).

Grants

2012 Grant-in-Aid for Young Scientists (B)