Hayashi E, Cho Y, Inoue M, Murakami T, Hosoda T. The characterization of cardiac stem cells obtained from patients who have received left ventriculoplasty. Stem Cell Transl Invest. 2015; 2(1):e537-40.

Cho Y, Hosoda T, Tashiro R, Shimura S, Tanaka C, Ueda T.
Internal mammary arterio-cardiac venous shunt enhances angiogenesis of bone marrow mononuclear cells in swine.
Exp Clin Cardiol. 2014; in press.

Signore S, Sorrentino A, Ferreira-Martins J, Kannappan R, Shafaie M, Del Ben F, Isobe K, Arranto C, Wybieralska E, Webster A, Sanada F, Ogorek B, Zheng H, Liu X, Del Monte F, D'Alessandro DA, Wunimenghe O, Michler RE, Hosoda T, Goichberg P, Leri A, Kajstura J, Anversa P, Rota M.
Response to letter regarding article "inositol 1,4,5-trisphosphate receptors and human left ventricular myocytes".
Circulation. 2014 May 27;129(21):e510-1.

Sanada F, Kim J, Czarna A, Chan NY, Signore S, Ogorek B, Isobe K, Wybieralska EW, Borghetti G, Pesapane A, Sorrentino A, Mangano EN, Cappetta D, Mangiaracina CM, Ricciardi M, Cimini M, Ifedigbo E, Perrella MA, Goichberg P, Choi AM, Kajstura J, Hosoda T, Rota M, Anversa P, Leri A.
c-kit-positive cardiac stem cells nested in hypoxic niches are activated by stem cell factor reversing the aging myopathy.
Circ Res. 2014 Jan 3;114(1):41-55.

Signore S, Sorrentino A, Ferreira-Martins J, Kannappan R, Shafaie M, Del Ben F, Isobe K, Arranto C, Wybieralska E, Webster A, Sanada F, Ogorek B, Zheng H, Liu X, Del Monte F, D'Alessandro DA, Wunimenghe O, Michler RE, Hosoda T, Goichberg P, Leri A, Kajstura J, Anversa P, Rota M.
Inositol 1,4,5-triphosphate receptors and human left ventricular myocytes.
Circulation. 2013 Sep 17;128(12):1286-97.

Dey D, Han L, Bauer M, Sanada F, Oikonomopoulos A, Hosoda T, Unno K, De Almeida P, Leri A, Wu JC.
Dissecting the molecular relationship among various cardiogenic progenitor cells.
Circ Res. 2013 Apr 26;112(9):1253-62.

Kajstura J, Bai Y, Cappetta D, Kim J, Arranto C, Sanada F, D’Amario D, Matsuda A, Bardelli S, Ferreira-Martins J, Hosoda T, Leri A, Rota M, Loscalzo J, Anversa P.
Tracking chromatid segregation to identify human cardiac stem cells that regenerate extensively the infarcted myocardium.
Circ Res. 2012 Sep 14;111(7):894-906.

Ferreira-Martins J, Ogorek B, Cappetta D, Matsuda A, Signore S, D'Amario D, Kostyla J, Steadman E, Ide-Iwata N, Sanada F, Iaffaldano G, Ottolenghi S, Hosoda T, Anversa P, Leri A, Kajstura J, Rota M.
Cardiomyogenesis in the developing heart is regulated by c-kit-positive cardiac stem cells.
Circ Res. 2012 Mar 2;110(5):701-15.

Kajstura J, Rota M, Hosoda T, Anversa P, Leri A.
Response to Bergmann et al: Carbon 14 Birth Dating of Human Cardiomyocytes.
Circ Res. 2012 Jan 6;110(1):e19-e21.

Bolli R, Chugh AR, D'Amario D, Loughran JH, Stoddard MF, Ikram S, Beache GM, Wagner SG, Leri A, Hosoda T, Sanada F, Elmore JB, Goichberg P, Cappetta D, Solankhi NK, Fahsah I, Rokosh DG, Slaughter MS, Kajstura J, Anversa P.
Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO):
initial results of a randomized phase 1 trial.
Lancet. 2011 Nov 26;378(9806):1847-57.

Hosoda T, Zheng H, Cabral-da-Silva MC, Sanada F, Ide-Iwata N, Ogorek B, Ferreira-Martins J, Arranto C, D'Amario D, Del Monte F, Urbanek K, D'Alessandro DA, Michler RE, Anversa P, Rota M, Kajstura J, Leri A.
Response to letter regarding article, “Human cardiac stem cell differentiation is regulated by a mircrine mechanism”.
Circulation. 2011 Oct 25;124(17):e457.

Cesselli D, Beltrami AP, D'Aurizio F, Marcon P, Bergamin N, Toffoletto B, Pandolfi M, Puppato E, Marino L, Signore S, Livi U, Verardo R, Piazza S, Marchionni L, Fiorini C, Schneider C, Hosoda T, Rota M, Kajstura J, Anversa P, Beltrami CA, Leri A.
Effects of age and heart failure on human cardiac stem cell function.
Am J Pathol. 2011 Jul;179(1):349-66.

D'Amario D, Cabral-Da-Silva MC, Zheng H, Fiorini C, Goichberg P, Steadman E, Ferreira-Martins J, Sanada F, Piccoli M, Cappetta D, D'Alessandro DA, Michler RE, Hosoda T, Anastasia L, Rota M, Leri A, Anversa P, Kajstura J.
Insulin-like growth factor-1 receptor identifies a pool of human cardiac stem cells with superior therapeutic potential for myocardial regeneration.
Circ Res. 2011 Jun 10;108(12):1467-81.

Kajstura J, Rota M, Hall SR, Hosoda T, D'Amario D, Sanada F, Zheng H, Ogorek B, Rondon-Clavo C, Ferreira-Martins J, Matsuda A, Arranto C, Goichberg P, Giordano G, Haley KJ, Bardelli S, Rayatzadeh H, Liu X, Quaini F, Liao R, Leri A, Perrella MA, Loscalzo J, Anversa P.
Evidence for human lung stem cells.
N Engl J Med. 2011 May 12;364(19):1795-806.

Goichberg P, Bai Y, D'Amario D, Ferreira-Martins J, Fiorini C, Zheng H, Signore S, del Monte F, Ottolenghi S, D'Alessandro DA, Michler RE, Hosoda T, Anversa P, Kajstura J, Rota M, Leri A.
The ephrin A1-EphA2 system promotes cardiac stem cell migration after infarction.
Circ Res. 2011 Apr 29;108(9):1071-83.

D'Amario D, Fiorini C, Campbell PM, Goichberg P, Sanada F, Zheng H, Hosoda T, Rota M, Connell JM, Gallegos RP, Welt FG, Givertz MM, Mitchell RN, Leri A, Kajstura J, Pfeffer MA, Anversa P.
Functionally competent cardiac stem cells can be isolated from endomyocardial biopsies of patients with advanced cardiomyopathies.
Circ Res. 2011 Apr 1;108(7):857-61.

Hosoda T*, Zheng H, Cabral-da-Silva M, Sanada F, Ide-Iwata N, Ogorek B, Ferreira-Martins J, Arranto C, D'Amario D, del Monte F, Urbanek K, D'Alessandro DA, Michler RE, Anversa P, Rota M, Kajstura J, Leri A*.
Human cardiac stem cell differentiation is regulated by a mircrine mechanism.
Circulation. 2011 Mar 29;123(12):1287-96.
(*: corresponding author)

Kajstura J, Gurusamy N, Ogorek B, Goichberg P, Clavo-Rondon C, Hosoda T, D'Amario D, Bardelli S, Beltrami AP, Cesselli D, Bussani R, del Monte F, Quaini F, Rota M, Beltrami CA, Buchholz BA, Leri A, Anversa P.
Myocyte turnover in the aging human heart.
Circ Res. 2010 Nov 26;107(11):1374-86.

Urbanek K, Cabral-da-Silva MC, Ide-Iwata N, Maestroni S, Delucchi F, Zheng H, Ferreira-Martins J, Ogorek B, D'Amario D, Bauer M, Zerbini G, Rota M, Hosoda T, Liao R, Anversa P, Kajstura J, Leri A.
Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.
Circ Res. 2010 Aug 6;107(3):429-41.

Kajstura J, Urbanek K, Perl S, Hosoda T, Zheng H, Ogorek B, Ferreira-Martins J, Goichberg P, Rondon-Clavo C, Sanada F, D'Amario D, Rota M, Del Monte F, Orlic D, Tisdale J, Leri A, Anversa P.
Cardiomyogenesis in the adult human heart.
Circ Res. 2010 Jul 23;107(2):305-15.

De Angelis A, Piegari E, Cappetta D, Marino L, Filippelli A, Berrino L, Ferreira-Martins J, Zheng H, Hosoda T, Rota M, Urbanek K, Kajstura J, Leri A, Rossi F, Anversa P.
Anthracycline cardiomyopathy is mediated by depletion of the cardiac stem cell pool and is rescued by restoration of progenitor cell function.
Circulation. 2010 Jan 19;121(2):276-92.

D'Alessandro DA, Kajstura J, Hosoda T, Gatti A, Bello R, Mosna F, Bardelli S, Zheng H, D'Amario D, Padin-Iruegas ME, Carvalho AB, Rota M, Zembala MO, Stern D, Rimoldi O, Urbanek K, Michler RE, Leri A, Anversa P.
Progenitor cells from the explanted heart generate immunocompatible myocardium within the transplanted donor heart.
Circ Res. 2009 Nov 20;105(11):1128-40.

Ferreira-Martins J, Rondon-Clavo C, Tugal D, Korn JA, Rizzi R, Padin-Iruegas ME, Ottolenghi S, De Angelis A, Urbanek K, Ide-Iwata N, D'Amario D, Hosoda T, Leri A, Kajstura J, Anversa P, Rota M.
Spontaneous calcium oscillations regulate human cardiac progenitor cell growth.
Circ Res. 2009 Oct 9;105(8):764-74.

Hosoda T, D'Amario D, Cabral-Da-Silva MC, Zheng H, Padin-Iruegas ME, Ogorek B, Ferreira-Martins J, Yasuzawa-Amano S, Amano K, Ide-Iwata N, Cheng W, Rota M, Urbanek K, Kajstura J, Anversa P, Leri A.
Clonality of mouse and human cardiomyogenesis in vivo.
Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17169-74.

Bearzi C, Leri A, Lo Monaco F, Rota M, Gonzalez A, Hosoda T, Pepe M, Qanud K, Ojaimi C, Bardelli S, D'Amario D, D'Alessandro DA, Michler RE, Dimmeler S, Zeiher AM, Urbanek K, Hintze TH, Kajstura J, Anversa P.
Identification of a coronary vascular progenitor cell in the human heart.
Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15885-90.

Padin-Iruegas ME, Misao Y, Davis ME, Segers VF, Esposito G, Tokunou T, Urbanek K, Hosoda T, Rota M, Anversa P, Leri A, Lee RT, Kajstura J.
Cardiac progenitor cells and biotinylated insulin-like growth factor-1 nanofibers improve endogenous and exogenous myocardial regeneration after infarction.
Circulation. 2009 Sep 8;120(10):876-87.

Boni A, Urbanek K, Nascimbene A, Hosoda T, Zheng H, Delucchi F, Amano K, Gonzalez A, Vitale S, Ojaimi C, Rizzi R, Bolli R, Yutzey KE, Rota M, Kajstura J, Anversa P, Leri A.
Notch1 regulates the fate of cardiac progenitor cells.
Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15529-34.

Rota M, Padin-Iruegas ME, Misao Y, De Angelis A, Maestroni S, Ferreira-Martins J, Fiumana E, Rastaldo R, Arcarese ML, Mitchell TS, Boni A, Bolli R, Urbanek K, Hosoda T, Anversa P, Leri A, Kajstura J.
Local activation or implantation of cardiac progenitor cells rescues scarred infarcted myocardium improving cardiac function.
Circ Res. 2008 Jul 3;103(1):107-16.

Siddiqi S, Gude N, Hosoda T, Muraski J, Rubio M, Emmanuel G, Fransioli J, Vitale S, Parolin C, D'Amario D, Schaefer E, Kajstura J, Leri A, Anversa P, Sussman MA.
Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge.
Circ Res. 2008 Jul 3;103(1):89-97.

Gonzalez A, Rota M, Nurzynska D, Misao Y, Tillmanns J, Ojaimi C, Padin-Iruegas ME, Muller P, Esposito G, Bearzi C, Vitale S, Dawn B, Sanganalmath SK, Baker M, Hintze TH, Bolli R, Urbanek K, Hosoda T, Anversa P, Kajstura J, Leri A.
Activation of cardiac progenitor cells reverses the failing heart senescent phenotype and prolongs lifespan.
Circ Res. 2008 Mar 14;102(5):597-606.

Tillmanns J, Rota M, Hosoda T, Misao Y, Esposito G, Gonzalez A, Vitale S, Parolin C, Yasuzawa-Amano S, Muraski J, De Angelis A, Lecapitaine N, Siggins RW, Loredo M, Bearzi C, Bolli R, Urbanek K, Leri A, Kajstura J, Anversa P.
Formation of large coronary arteries by cardiac progenitor cells.
Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1668-73.

Rota M, Kajstura J, Hosoda T, Bearzi C, Vitale S, Esposito G, Iaffaldano G, Padin-Iruegas ME, Gonzalez A, Rizzi R, Small N, Muraski J, Alvarez R, Chen X, Urbanek K, Bolli R, Houser SR, Leri A, Sussman MA, Anversa P.
Bone marrow cells adopt the cardiomyogenic fate in vivo.
Proc Natl Acad Sci U S A. 2007 Nov 6;104(45):17783-8.

Bearzi C, Rota M, Hosoda T, Tillmanns J, Nascimbene A, De Angelis A, Yasuzawa-Amano S, Trofimova I, Siggins RW, Lecapitaine N, Cascapera S, Beltrami AP, D'Alessandro DA, Zias E, Quaini F, Urbanek K, Michler RE, Bolli R, Kajstura J, Leri A, Anversa P.
Human cardiac stem cells.
Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):14068-73.

Rota M, Hosoda T, De Angelis A, Arcarese ML, Esposito G, Rizzi R, Tillmanns J, Tugal D, Musso E, Rimoldi O, Bearzi C, Urbanek K, Anversa P, Leri A, Kajstura J.
The young mouse heart is composed of myocytes heterogeneous in age and function.
Circ Res. 2007 Aug 17;101(4):387-99.

Chen X, Wilson RM, Kubo H, Berretta RM, Harris DM, Zhang X, Jaleel N, MacDonnell SM, Bearzi C, Tillmanns J, Trofimova I, Hosoda T, Mosna F, Cribbs L, Leri A, Kajstura J, Anversa P, Houser SR.
Adolescent feline heart contains a population of small, proliferative ventricular myocytes with immature physiological properties.
Circ Res. 2007 Mar 2;100(4):536-44.

Rota M, LeCapitaine N, Hosoda T, Boni A, De Angelis A, Padin-Iruegas ME, Esposito G, Vitale S, Urbanek K, Casarsa C, Giorgio M, Luscher TF, Pelicci PG, Anversa P, Leri A, Kajstura J.
Diabetes promotes cardiac stem cell aging and heart failure, which are prevented by deletion of the p66shc gene.
Circ Res. 2006 Jul 7;99(1):42-52.

Urbanek K, Cesselli D, Rota M, Nascimbene A, De Angelis A, Hosoda T, Bearzi C, Boni A, Bolli R, Kajstura J, Anversa P, Leri A.
Stem cell niches in the adult mouse heart.
Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9226-31.

Monzen K*, Hosoda T*, Hayashi D, Imai Y, Okawa Y, Kohro T, Uozaki H, Nishiyama T, Fukayama M, Nagai R.
The use of a supercooling refrigerator improves the preservation of organ grafts.
Biochem Biophys Res Commun. 2005 Nov 18;337(2):534-9.
(*: contributed equally)

Urbanek K, Rota M, Cascapera S, Bearzi C, Nascimbene A, De Angelis A, Hosoda T, Chimenti S, Baker M, Limana F, Nurzynska D, Torella D, Rotatori F, Rastaldo R, Musso E, Quaini F, Leri A, Kajstura J, Anversa P.
Cardiac stem cells possess growth factor-receptor systems that after activation regenerate the infarcted myocardium, improving ventricular function and long-term survival.
Circ Res. 2005 Sep 30;97(7):663-73.

Kajstura J, Rota M, Whang B, Cascapera S, Hosoda T, Bearzi C, Nurzynska D, Kasahara H, Zias E, Bonafe M, Nadal-Ginard B, Torella D, Nascimbene A, Quaini F, Urbanek K, Leri A, Anversa P.
Bone marrow cells differentiate in cardiac cell lineages after infarction independently of cell fusion.
Circ Res. 2005 Jan 7;96(1):127-37.

Monzen K, Zhu W, Kasai H, Hiroi Y, Hosoda T, Akazawa H, Zou Y, Hayashi D, Yamazaki T, Nagai R, Komuro I.
Dual effects of the homeobox transcription factor Csx/Nkx2-5 on cardiomyocytes.
Biochem Biophys Res Commun. 2002 Nov 8;298(4):493-500.

Ikeda Y, Hiroi Y, Hosoda T, Utsunomiya T, Matsuo S, Ito T, Inoue J, Sumiyoshi T, Takano H, Nagai R, Komuro I.
Novel point mutation in the cardiac transcription factor CSX/NKX2.5 associated with congenital heart disease.
Circ J. 2002 Jun;66(6):561-3.

Hosoda T, Monzen K, Hiroi Y, Oka T, Takimoto E, Yazaki Y, Nagai R, Komuro I.
A novel myocyte-specific gene Midori promotes the differentiation of P19CL6 cells into cardiomyocytes.
J Biol Chem. 2001 Sep 21;276(38):35978-89.

Monzen K, Hiroi Y, Kudoh S, Akazawa H, Oka T, Takimoto E, Hayashi D, Hosoda T, Kawabata M, Miyazono K, Ishii S, Yazaki Y, Nagai R, Komuro I.
Smads, TAK1, and their common target ATF-2 play a critical role in cardiomyocyte differentiation.
J Cell Biol. 2001 May 14;153(4):687-98.

Hiroi Y, Chen R, Sawa H, Hosoda T, Kudoh S, Kobayashi Y, Aburatani H, Nagashima K, Nagai R, Yazaki Y, Medof ME, Komuro I.
Cloning of murine glycosyl phosphatidylinositol anchor attachment protein, GPAA1.
Am J Physiol Cell Physiol. 2000 Jul;279(1):C205-12.

Monzen K, Shiojima I, Hiroi Y, Kudoh S, Oka T, Takimoto E, Hayashi D, Hosoda T, Habara-Ohkubo A, Nakaoka T, Fujita T, Yazaki Y, Komuro I.
Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4.
Mol Cell Biol. 1999 Oct;19(10):7096-105.

Hosoda T, Komuro I, Shiojima I, Hiroi Y, Harada M, Murakawa Y, Hirata Y, Yazaki Y.
Familial atrial septal defect and atrioventricular conduction disturbance associated with a point mutation in the cardiac homeobox gene CSX/NKX2-5 in a Japanese patient.
Jpn Circ J. 1999 May;63(5):425-6.

Hiroi Y, Komuro I, Matsushita I, Aburatani H, Hosoda T, Nakahori Y, Medof ME, Yazaki Y.
Assignment of the human GPAA1 gene, which encodes a product required for the attachment of glycosylphosphatidylinositols to proteins, at 8q24.
Genomics. 1998 Dec 1;54(2):354-5.

Hiroi Y, Komuro I, Chen R, Hosoda T, Mizuno T, Kudoh S, Georgescu SP, Medof ME, Yazaki Y.
Molecular cloning of human homolog of yeast GAA1 which is required for attachment of glycosylphosphatidylinositols to proteins.
FEBS Lett. 1998 Jan 16;421(3):252-8.

Hosoda T, Toba K, Nagase T, Kozaki K, Hosoi T, Ohga E, Katayama H, Sudo E, Matsuse T, Fukuchi Y, Ouchi Y, Orimo H.
A case of pulmonary infiltration with eosinophilia (PIE) syndrome associated with syndrome of inappropriate secretion of ADH (SIADH) in the elderly patient.
Nihon Ronen Igakkai Zasshi. 1995 Oct;32(10):670-4.

Hayashi E, Hosoda T.
How do resident stem cells repair the damaged myocardium?
World J Stem Cells. 2015 Jan 26;7(1):182-5.

Leri A, Rota M, Hosoda T, Goichberg P, Anversa P.
Cardiac stem cell niches.
Stem Cell Res. 2014 Nov;13(3):631-46.

Hayashi E, Hosoda T.
Myocyte renewal and therapeutic myocardial regeneration using various
progenitor cells.
Heart Fail Rev. 2014 Nov;19(6):789-97.

Hosoda T.
Myocardial repair by resident stem cells; the potential mechanism of action.
J Cardiol Ther. 2014 Aug 10;1(7): 150-3.

Hayashi E, Hosoda T.
Development of Cardiovascular Regenerative Medicine.
medicina. 2014 Apr;51(4): 718-21.

Hosoda T.
Clinical application of cardiac stem cells.
Cell Biol: Res Ther. 2013 Nov;S1:ID 1567, 2 pages.

Hosoda T.
The mircrine mechanism controlling cardiac stem cell fate.
Front Genet. 2013 Oct 10;4:204.

Hayashi E, Hosoda T.
Therapeutic application of cardiac stem cells and other cell types.
Biomed Res Int. 2013 Jun;2013:ID 736815, 6 pages.

Hayashi E, Hosoda T.
Regenerative Medicine: Progress and Prospect of Cell Therapy.
Curr Ther. 2013 Apr;31(4):406-11.

Hayashi E, Tanaka C, Hosoda T.
Cardiac Stem Cell and Aging.
Heart View. 2013 Apr;17(4):379-84.

Hayashi E, Hosoda T.
Cardiac-specific Tissue Stem Cells.
Vasc Biol Med. 2013 Mar;14(1):77-84.

Hosoda T.
Clinical applications of cardiac stem cells.
Shinzo. 2012 Aug;44(8):1095-8.

Hosoda T.
c-kit-positive cardiac stem cell differentiation regulated by microRNA.
Cardioangiology. 2012 Apr;71(4):355-9.

Hosoda T.
Editorial: The Heart heals itself.
Anatom Physiol. 2012 Jan;2(1):e112.

Hosoda T.
c-kit-positive cardiac stem cells and myocardial regeneration.
Am J Cardiovasc Dis. 2012 Jan 1;2(1):58-67.

Leri A, Hosoda T, Kajstura J, Anversa P, Rota M.
Identification of a coronary stem cell in the human heart.
J Mol Med (Berl). 2011 Oct;89(10):947-59.

Hosoda T, Rota M, Kajstura J, Leri A, Anversa P.
Role of stem cells in cardiovascular biology.
J Thromb Haemost. 2011 Jul;9 Suppl 1:151-61.

Hosoda T.
Brigham and Women’s Hospital, Harvard Medical School.
Regenerative Medicine. 2010 Nov;9(4):83-5.

Hosoda T.
Cardiac regeneration-Up-date.
Angiology Frontier. 2010 Mar;9(1):54-61.

Hosoda T, Kajstura J, Leri A, Anversa P.
Mechanisms of myocardial regeneration.
Circ J. 2010 Jan;74(1):13-7.

Hosoda T.
Biology of cardiac stem cells.
Journal of Clinical and Experimental Medicine. 2010 Jan;232(5):606-14.

Hosoda T.
Perspective of cardiac regeneration.
Cardioangiology. 2009 Oct;66(4):408-18.

Kajstura J, Urbanek K, Rota M, Bearzi C, Hosoda T, Bolli R, Anversa P, Leri A.
Cardiac stem cells and myocardial disease.
J Mol Cell Cardiol. 2008 Oct;45(4):505-13.

Kajstura J, Hosoda T, Bearzi C, Rota M, Maestroni S, Urbanek K, Leri A, Anversa P.
The human heart: a self-renewing organ.
Clin Transl Sci. 2008 May;1(1):80-6.

Hosoda T.
Cardiac stem cell therapy for the failing heart.
Japanese Heart Failure Society News Letter. 2008 Apr;12(4):9-13.

Leri A, Hosoda T, Rota M, Kajstura J, Anversa P.
Myocardial Regeneration by Exogenous and Endogenous Progenitor Cells.
Drug Discov Today Dis Mech. 2007 Sep;4(3):197-203.

Anversa P, Leri A, Rota M, Hosoda T, Bearzi C, Urbanek K, Kajstura J, Bolli R.
Concise review: stem cells, myocardial regeneration, and methodological artifacts.
Stem Cells. 2007 Mar;25(3):589-601.

Kajstura J, Rota M, Urbanek K, Hosoda T, Bearzi C, Anversa P, Bolli R, Leri A.
The telomere-telomerase axis and the heart.
Antioxid Redox Signal. 2006 Nov-Dec;8(11-12):2125-41.

Hosoda T.
Cell therapy of myocardial infarction.
Cardioangiology. 2006 Nov;60(5):463-9.

Hosoda T.
Meeting cardiac stem cells.
Molecular Cardiovascular Medicine. 2006 Jun;7(3):312-6.

Leri A, Hosoda T, Kajstura J, Anversa P.
Heart failure and regenerative cardiology.
Regen Med. 2006 Mar;1(2):153-9.

Anversa P, Rota M, Urbanek K, Hosoda T, Sonnenblick EH, Leri A, Kajstura J, Bolli R.
Myocardial aging--a stem cell problem.
Basic Res Cardiol. 2005 Nov;100(6):482-93.

Leri A, Rota M, Hosoda T, Anversa P. Cellular basis for myocardial regeneration and repair. In: Mann DL, Felker MG. Heart Failure: A Companion to Braunwald’s Heart Disease, 3rd Edition. (Elsevier, Philadelphia, PA) 2014;p.42-61.

Leri A, Boni A, Siggins R, Nascimbene A, Hosoda T.
Cardiac stem cells and their niches.
In: Leri A, Anversa P, Frishman WH. Cardiovascular Regeneration and Stem Cell Therapy. (Blackwell Futura, Malden, MA) 2007;p.87-94.

Research progress report at the Tokai University’s 5th Symposium for Tenure Track Program (at Tokai University Isehara Campus).

Poster presentation “GDF11 enhances proliferation of cardiac stem cells.”
at the 5th Molecular Cardiovascular Conference II (Kobe, Hyogo).

Poster presentation “GDF11 enhances proliferation of human cardiac stem cells.” at the Annual Congress of the European Society of Cardiology (Barcelona, Spain) .

Poster presentation “The Cardiac Rejuvenating Factor GDF11 Promotes the Proliferation of Endogenous Cardiac Stem Cells” at the 111th Annual Scientific Meeting of the Japanese Society of Internal Medicine (at Tokyo International Forum).

Presentation in a symposium “The Most Promising Cell Therapy for the Failing Heart and its Application in Japan” at the 78th Annual Scientific Meeting of the Japanese Circulation Society (at Tokyo International Forum).

Research progress report at the Tokai University’s 4th Symposium for Tenure Track Program (at Tokai University Isehara Campus).

Lecture “Identification of the third-generation cardiac stem cells and　their clinical application” at the 17th Annual Scientific Meeting of the Society of Cardiovascular Endocrinology and Metabolism (at Osaka).

Poster presentation “The Third-Generation Cardiac Stem Cell Therapy for the Failing Heart” at the 4th Molecular Cardiovascular Conference II (Kiroro, Hokkaido).

Presentation in a plenary session in English “The Third-Generation Cardiac Stem Cells Defined by Asymmetric Chromatid Segregation and “Mircrine” Mechanism Contributing to Myocardial Regeneration” at the 77th Annual Scientific Meeting of the Japanese Circulation Society (at Pacifico Yokohama, Kanagawa).

Research progress report at the Tokai University’s 3rd Symposium for Tenure Track Program (at Tokai University Takanawa Campus, Tokyo) .

Lecture “Topics: Cardiac Stem Cell Therapy for the Failing Heart” at the 16th Cardiac Nuclear Medicine Forum (at Tokyo Conference Center Shinagawa).

Keynote lecture “Cardiac Stem Cell Therapy for the Failing Heart” at the 13th Vascular and Brain Conference (at Osaka Teikoku Hotel).

Lecture “Cardiac Stem Cell Therapy for the Failing Heart” at the 51st Research Forum on Stem Cell Therapy (at the Institute of Medical Science, the University of Tokyo).

Lecture “Clinical application of cardiovascular regenerative medicine” at Shinjuku Cardiovascular Seminar (at Sakakibara Heart Institute, Tokyo)

Lecture “Say hello to the Cardiac Stem Cells” at the Boston Japanese Researchers Forum (at Cambridge, MA, USA)

Presentation in English ““Second-Generation” Cardiac Stem Cell Therapy for the Failing Heart” at the 76th Annual Scientific Meeting of the Japanese Circulation Society (at Fukuoka).

Lecture “Cardiac Stem Cell Therapy for the Failing Heart” at Cardiology Expert Meeting (at Keio University, Tokyo).

Lecture “Cardiac Stem Cell Therapy for Ischemic Heart Diseases” at Department of Cardiovascular Medicine, Tohoku University (at Sendai, Miyagi).

Research progress report at the Tokai University’s 2nd Symposium for Tenure Track Program (at Kasumigaseki, Tokyo).

Lecture in English “Myocardial regeneration utilizing “superior” cardiac stem cells” at the 28th Annual Meeting of the International Society for Heart Research (ISHR) Japanese Section (at Tokyo).

Lecture “Cardiac Stem Cell and Myocardial Regeneration” at the 4th Translational Research Conference (at Nihon University, Tokyo).

Presentation in English “Myocyte Turnover in the Adult Human Heart” at the 75th Annual Scientific Meeting of the Japanese Circulation Society (at Pacifico Yokohama, Kanagawa).

Presentation in English “Two Distinct Subpopulations of Adult Human Cardiac Stem Cells Contribute to the Therapeutic Regeneration of the Failing Heart” at the 23rd Congress of the International Society on Thrombosis and Haemostasis (ISTH) (at Kyoto International Conference Center).

Lecture “Is it possible to regenerate coronary artery?” at the 24th Annual Scientific Meeting of the Japanese Coronary Association (at Tokyo Station Conference).

Lecture “Cardiac Stem Cell and Regeneration” at Sakakibara Heart Institute (at Tokyo).

Lecture “The heart in the view of system biology” at the Research Center for Advanced Science and Technology, University of Tokyo (at Tokyo).

Lecture “Cardiac Stem Cell and Regeneration” at Department of Geriatrics, University of Tokyo (at Tokyo).

Invited Lecture “Senescence of Myocyte Progenitor Cells and Cardiac Regeneration” at the 74th Annual Scientific Meeting of the Japanese Circulation Society (at Kyoto International Conference Center).

Presentation in English “Differentiation of Cardiac Progenitor Cells into Myocytes is Regulated by miR-499” at the Scientific Sessions of the American Heart Association (at Orlando, FL, USA).

Lecture “Cardiac Stem Cell Therapy for the Failing Heart” at the 10th Annual Meeting of the New Wave (at Orlando, FL, USA).

Invited Lecture in English “Cardiac stem cell and cardiovascular diseases” at the 3rd Oriental Congress of Cardiology (at Shanghai International Conference Center, China).

Lecture “Cardiac Stem Cell Therapy for the Failing Heart” at Japanese Researchers’ Academic Network (JaRAN) (at Boston, MA, USA).

Lecture “Cardiac Stem Cell Therapy for the Failing Heart” at Department of Cardiovascular Medicine, University of Tokyo (at Tokyo).

Lecture “Cardiac Stem Cell Therapy for the Failing Heart” at Department of Geriatrics, University of Tokyo (at Tokyo).

Lecture in English “MicroRNA-499 Promotes the Differentiation of Cardiac Progenitor Cells into Myocytes” at the Biomedical Research Institute in the Brigham and Women’s Hospital (at Boston, MA, USA).

Lecture “Meeting Cardiac Stem Cells” at the Boston Japanese Researchers Forum (at Cambridge, MA, USA)

Presentation in English “MicroRNA-499 promotes the differentiation of cardiac progenitor cells into myocytes” at the Scientific Sessions of the American Heart Association (at New Orleans, LA, USA).

Presentation in English “Deregulation of microRNAs in the heart of c-kit-defective mice” at the Scientific Sessions of the American Heart Association (at Orlando, FL, USA).

Poster Presentation “Defects in the c-kit-SCF system have profound effects on myocardial gene expression” at the Scientific Sessions of the American Heart Association (at Orlando, FL, USA).

Presentation in English “Human cardiac progenitor cells” at the Scientific Sessions of the American Heart Association (at Chicago, IL, USA).

Presentation in English “The reconstitution of large coronary artery by cardiac stem cells is mediated by hypoxia” at the Scientific Sessions of the American Heart Association (at Chicago, IL, USA).

Presentation in English “Human cardiac progenitor cells are multipotent and differentiate into myocytes and vascular cells in vivo” (title had been changed from the originally submitted “Human cardiac progenitor cells regenerate cardiomyocytes and coronary vessels repairing the infarcted heart” due to better findings) at the Scientific Sessions of the American Heart Association (at Chicago, IL, USA).

Presentation in English “Molecular phenotype of senescent myocytes” at the Scientific Sessions of the American Heart Association (at Dallas, TX, USA).

Lecture “Infectious Disease” at the Outline of Clinical Medicine Series organized by the University of Tokyo Graduate School of Medicine (at Tokyo) (broadcasted on cable TV).

Lecture “Renal Disease and Dialysis” at the Outline of Clinical Medicine Series organized by the University of Tokyo Graduate School of Medicine (at Tokyo) (broadcasted on cable TV).

Presentation “A novel myocyte-specific gene Midori promotes the differentiation of P19CL6 cells into cardiomyocytes” at the Molecular Cardiovascular Conference (at Hokkaido).

Presentation “Cloning of a novel gene which is expressed in the very early stage of cardiomyocyte differentiation” at the Annual Scientific Meeting of the Japanese Circulation Society (at Osaka).

Presentation in English “Cloning of a novel gene which is expressed in the very early stage of cardiomyocyte differentiation” at the Scientific Sessions of the American Heart Association (at Atlanta, GA, USA).

Presentation “Cloning of a novel gene which is expressed in the very early stage of cardiomyocyte differentiation” at the Molecular Cardiovascular Conference (at Hokkaido).

2015 Japan Agency for Medical Research and Development (AMED) Research on Regenerative Medicine for Clinical Application, Role: PI
“Autologous Cardiac Stem Cell Therapy for Severe Chronic Ischemic Heart Failure Patients: the JOKER Trial”

2015 The Vehicle Racing Commemorative Foundation (VECOF) Grants-in-Aid for Basic and Innovative Medical Research, Role: PI
“Investigate the cell biological mechanism of cardiac rejuvenation by GDF11”

2013 Grants-in-Aid for Scientific Research (C) (JSPS) Role: PI
“Establishment of the method to differentiate human cardiac stem cells into　cardiomyocytes”

2011 Grants-in-Aid for Research Activity Start-up (JSPS) Role: PI
“Isolation and culture of c-kit-positive human cardiac stem cells (CSCs): Aiming for the first clinical trial in Japan”

2009 R21HL094894-S1 (ARRA/NIH/NHLBI) Role: PI
Micro-RNA and Differentiation of Cardiac Progenitor Cells.

2008 R21HL094894 (NIH/NHLBI) Role: PI
Micro-RNA and Differentiation of Cardiac Progenitor Cells.

2008 P01HL092868 (NIH/NHLIBI) Role: Co-Investigator
Restructuring the Transplanted Heart (PI: Dr. Piero Anversa).

2007 R01HL065577 (NIH/NHLBI) Role: Co-Investigator
Bone Marrow and Cardiac Progenitor Cells in Cardiac Repair (PI: Dr. Annarosa Leri).